Jane and Jerome Schultz Lectureship in Engineering
PLEASE JOIN US FOR THE
THIRD SCHULTZ LECTURE
Presented by: Jennifer Lippincott-Schwartz
Looking Under the Hood of Cells from Micron to Atomic Scales
Abstract:
Powerful new ways to image the internal structures and complex dynamics of cells are revolutionizing cell biology and biomedical research. In my talk, I will focus on three emerging technologies capable of revealing new properties of cellular organization at scales ranging from nanometers to atomic resolution.
- Whole cell milling using Focused Ion Beam Electron Microscopy (FIB-SEM) was used to reconstruct the entire cell volume at 4-nm voxel resolution, revealing all membrane-bound organelles and their trafficking intermediates at isotropic resolution.
- Single particle tracking using Halo dyes revealed unexpected features of mRNA trafficking, including sites where secretory proteins are translated on ER and their regulation by lysosomes.
- High Resolution Template Matching (HRTM) of ribosome subunits in cryo-EM images of intact human cells afforded a look at ribosomes at different stages of peptide elongation at the atomic scale.
Together, these new tools open up a plethora of questions related to mechanisms of cell structure/function that can now be studied in intact cells at the nanometric/molecular level.
Event Information:
Thursday, January 22, 2026
Check-in for in-person registrants: 10:30 - 11:00 a.m.
Location: The University of California, Riverside
Alumni and Visitors Center
3701 Canyon Crest Drive
Riverside, CA 92521
Register:
To attend in person,
To attend the Zoom session,
If you registered before 12/12/25, please submit another Zoom RSVP
About Dr. Jennifer Lippincott-Schwartz
Dr. Jennifer Lippincott-Schwartz is a Senior Group Leader at the Howard Hughes Medical Institute’s Janelia Research Campus and Head of the Research Program on 4D Cellular Physiology. Lippincott-Schwartz has pioneered the use of green fluorescent protein technology for quantitative analysis and modelling of intracellular protein traffic and organelle dynamics in live cells. Her innovative techniques to label, image, quantify and model specific live cell protein populations and track their fate have provided vital tools used throughout the research community. Her findings using these techniques have reshaped thinking about the biogenesis, function, targeting, and maintenance of various subcellular organelles and macromolecular complexes and their crosstalk with regulators of the cell cycle, metabolism, aging, and cell fate determination. She is an elected member of the National Academy of Sciences, the National Academy of Medicine, the American Society of Arts and Sciences and the European Molecular Biology Organization. She is also a Fellow of The Biophysical Society, The Royal Microscopical Society and The American Society of Cell Biology. Her awards include the E.B. Wilson Medal of the American Society of Cell Biology, the Newcomb Cleveland Prize of the American Association for the Advancement of Science, the Van Deenen Medal, the Keith Porter Award of the American Society of Cell Biology, the Feodor Lynen Medal, and the Feulgen Prize of the Society of Histochemistry. She co-authored the textbook “Cell Biology” and was President of the American Society of Cell Biology. Dr. Lippincott-Schwartz attended Swarthmore College, received her MS from Stanford University, and obtained her PhD in Biochemistry from Johns Hopkins University.
About the Jane and Jerome Schultz Lectureship in Engineering
Jane and Jerome Schultz shared a lifelong passion for scientific research and its applications in health and medicine. At UCR, Jane as Director of Research Development and Jerry as the Founding Chair of the Department of Bioengineering, advanced UCR’s research agenda. The Schultz family established this Lectureship in Engineering in Jane’s memory and as a lasting legacy of their commitment to the education of future researchers and engineers.
In accordance with the mission of the Marlan and Rosemary Bourns College of Engineering (BCOE), the Jane and Jerome Schultz Lectureship in Engineering supports campus appearances by nationally and internationally known distinguished speakers. These annual lectures are open to students, faculty, staff, alumni, and community members free of charge. They focus on research and timely issues in the fields engineering and bioengineering to enhance the knowledge, understanding and experience of faculty and students by sparking discussions and intellectual exchange of ideas.